![]() If these drugs don’t work, there are other drugs that may help, but they should only be prescribed by someone who specialises in managing spasticity. You will usually be prescribed baclofen or tizanidine first. You may also find that it becomes easier to straighten or bend your affected limbs, and you may notice fewer muscle spasms. When your muscles are relaxed they can move more easily and you can stretch them further. They all work in slightly different ways, but they all help to relax your muscles. There are different types of drugs that you could be given. If you have generalised spasticity, or if botulinum toxin A treatment doesn’t reduce spasticity in the injected muscle, other types of medication can help reduce the stiffness and pain that often comes with spasticity. You should also have an assessment three to four months after the treatment, and be offered further injections if they are considered helpful. The treatment should be given with further rehabilitation such as physiotherapy, or other treatments like splinting or casting to ensure that any range gained in the muscle is maintained. The muscle-relaxing effects of botulinum toxin type A usually last for about three months, and you shouldn't notice any changes in sensation in your muscles. This treatment is mainly used for post-stroke spasticity in the hands, wrists and ankles. This reduces muscle tone (makes the muscle less tight), which can help you to straighten out your limbs. Botulinum toxin type A works by blocking the action of the nerves on the muscle, reducing your muscle’s ability to contract. The main brand names used for this treatment are Botox, Dysport and Xeomin. You may be given botulinum toxin type A as an injection directly into your muscle. Your physiotherapist will gently place your affected limb into as many different positions as possible using techniques called positioning, passive movement and active movement. This will help to stretch your muscles, keeping them flexible and reducing the possibility of contractures. If you have spasticity you should have physiotherapy every day to move your joints. Treatments may include a combination of physiotherapy, injections of botulinum toxin type A, and other medications. If you have muscle weakness after your stroke you should be assessed for spasticity, and receive therapy to reduce the risk of contractures. Find out more about the Stroke Association See all.Find out more ways to get involved See all.Find out more about the support we offer See all.Spinal cord stimulation (SCS), peripheral nerve stimulation (PNS) and transcutaneous electrical nerve stimulation (TENS) are some of the therapies that may be used to help relieve residual limb pain. These treatments use electrical stimulation on a nerve to relieve pain. They can help reduce residual limb pain and may help to diagnose a neuroma if the block stops the pain. These injections block or turn off a nerve's pain signals. A small study found that three sessions of hypnosis reduced residual limb pain in people with the condition. Gentle massaging of the limb can sometimes reduce pain. Wearing compression garments on the residual limb may also help. These therapies involve exercises done before and after amputation, as well as proper fitting and use of your prosthesis. They can also cause significant side effects. While they're very effective in reducing pain, the benefits don't last very long. They're usually given as topical medications applied to your skin. ![]() These drugs, including ketamine, block events that increase sensitivity in the neurons. N-methyl-D-aspartic acid (NMDA) agonists. ![]() It's thought that these drugs interfere with the transmission of nerve signals to reduce pain. Gabapentin (Gralise, Neurontin) and pregabalin (Lyrica) may help relieve pain caused by damage to the nerve fibers. Tricyclic antidepressants or selective norepinephrine reuptake inhibitors may help with pain caused by damage to the nerve fibers. These may be most helpful for pain resulting from problems with the skin, soft tissues, muscles and bones. Stronger medications, such as opioids, may be needed. Acetaminophen (Tylenol, others) and nonsteroidal anti-inflammatory drugs may help. Treatment options for residual limb pain may involve medications, including In about half of people with residual limb pain, the pain eventually improves without treatment. Treatment for residual limb pain focuses on treating the underlying cause of the pain, if possible.
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